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MASH (Fatty Liver Disease) Clinical Trial

Metabolic dysfunction-associated steatohepatitis (MASH) is the most severe form of non-alcoholic fatty liver disease. It may develop when fat builds up in the cells of the liver, causing inflammation and stiffness.

About 12% of UK adults have MASH—but many don’t know it! MASH is sometimes referred to as a silent killer and its symptoms are often non-specific making it difficult to diagnose, therefore you may not know you have the condition until the disease is at an advanced stage.

We are currently enrolling adult volunteers to participate in our clinical trials focused on investigational treatments for MASH, a type of fatty liver disease. If you have been diagnosed with MASH [with liver fibrosis] or have risk factors like Type 2 Diabetes, high blood pressure, high cholesterol, or obesity, then one of our clinical trials may be suitable for you.

Eligible participants may:

  • Receive regular monitoring at trial visits and access to our medical team if needed.
  • Receive confirmation and diagnosis of MASH for those not yet diagnosed.
  • Receive access to an investigational medication that may help advance future treatments for MASH.
  • Have the results of any additional investigations undertaken with the results also forwarded to their GP.
  • Receive trial-related health screening including Blood tests, Fibroscan, MRI Scan, etc.
  • Help future generations by contributing to medical research.

For further information and to discuss your eligibility with our team, please complete our online form.

Register your interest


When you register your interest with Accellacare (which is part of ICON plc), our team will review your information and connect you with studies that you may be eligible for. When we find a match, Accellacare clinical research specialists will contact you directly for further pre-screening. Please see our Privacy Policy for further details.


Data Protection

ICON plc is the data controller of the personal data, including health data, you choose to provide. We rely on your consent to use this information to identify potentially appropriate clinical trials for you and contact you about them. When we call you for further pre-screening, note that these calls will be recorded.

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Please note: You may or may not benefit medically from taking part and you are able to opt-out at any time and do not have to give us a reason for doing so. Your GP will be informed about your participation and all medical assessments that will be carried out as part of the trial. If during screening any abnormal results are found, you and your GP will also be informed.